Colon Cancer

Colorectal cancer is the third most common cancer in the UK, with an annual incidence of approximately 40,000 new cases. It is the second most common cause of cancer death in the UK.

Download this poster to read more about our work around the colon cancer pathway.

The main method currently used to diagnose colorectal cancer is optical colonoscopy. Approximately 440,000 procedures are carried out in the UK each year, requiring specialist input from gastroenterologists and surgeons. This is an invasive procedure, and there are considerable capacity issues in the UK, with patients commonly waiting between four and six weeks for a colonoscopy.

Within Guy’s and St Thomas’ Trust, colon cancer is one of the two most difficult areas in terms of delivering cancer targets. Furthermore, new NICE guidelines published in June 2015 have broadened the inclusion criteria for urgent cancer referrals for patients who are symptomatic for colon cancer. This means an increased number of urgent ‘2 Week Wait’ referrals to the Trust.

In consultation with clinicians, TOHETI has proposed that the diagnostic pathway for patients who are referred for suspicious colon cancer should include CT colonography (CTE scan) as first line of investigation for patients who meet certain criteria e.g. change in bowel habit ( constipation or diarrhea that is lasting less than 6weeks)(

It is anticipated that CT colonography will enable an accurate and quicker diagnosis and if needed, move to subsequent treatment. Patients referred for a CT colonography under the new pathway will meet the same revised clinical inclusion criteria as those set by NICE.

Proposed benefits to patient outcome/experience:

  • To increase early detection and improve prognosis.
  • To lower risks and discomfort to patient, through increased use of a minimally invasive technique.
  • To reduce the number of unnecessary optical colonoscopies.
  • Address capacity issues, and release optical colonoscopy capacity to focus on high-risk patients.

‘It is well established in the literature that CT colonography has an equivalent diagnostic accuracy to optical colonoscopy in the detection of medium sized polyps and cancers in the large bowel. At present it is an under utilised resource in our trust. This study will offer improved access to CT colonography as a non-invasive first line test for patients with large bowel symptoms. The outcome of this study will then help facilitate discussions on a revised Colon Cancer pathway in our trust, which should be more cost effective, with improved patient experience, and reduced waiting times.’ Nyree Griffin, Consultant Radiologist, Gastrointestinal imaging

Colon research study has recruited >160 patients so far and is currently recruiting!!

Colon cancer